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What is Chronic Diarrhea?

You may think that diarrhea is just, well, diarrhea. But if you have diarrhea that lasts longer than 4 weeks, it’s known as chronic diarrhea.1

Chronic diarrhea is a common problem. Up to 18% of Americans have loose stools more than 25% of the time, or experience more than 3 diarrhea episodes per day.1

What causes chronic diarrhea?

There are many different factors that can cause chronic diarrhea. In the United States, chronic diarrhea is often associated with1:

While it is not clear exactly how these conditions cause chronic diarrhea and loose stools, there is evidence that changes in the lining of the intestine can be caused by2:

  • Exposure to foreign substances (called external antigens), such as food ingredients like lactose
  • Toxins (that may be released from both “good” and “bad” bacteria)
  • Insults to the body (like infection)

When the environment inside your gut is functioning the way it should, it is called a stable environment. When substances (both foreign or natural) that may be toxic to the gut penetrate the lining of the intestine (also known as the gut barrier), it may upset this delicate balance, which can3,4:

  • Contribute to chronic diarrhea and loose stools in people with many different intestinal conditions
  • Prevent your body from properly absorbing nutrients from foods and fluid

How is the cause of chronic diarrhea diagnosed?

Diagnosing the underlying cause of chronic diarrhea can be challenging because diarrhea is a symptom that is associated with many different conditions.5

Your doctor will likely start by asking you questions about how long you have had diarrhea and how often you have episodes of diarrhea. You may also be asked about any recent travel to help determine if you may have picked up a parasite (or another infection-causing “bug”) somewhere. Then your doctor will probably do a physical exam and order blood testing. Stool testing may be ordered as well.5

The results of these tests will help your doctor determine if additional testing is needed to learn what could be causing your chronic diarrhea.5

Talking with your doctor

Talk to your doctor about getting help for chronic diarrhea and loose stools. Print out this free Doctor Discussion Guide to assist you, and learn how EnteraGam® may help manage chronic diarrhea and loose stools.

Once the cause of your chronic diarrhea and loose stools is correctly diagnosed, you can start to manage it, which may lead to fewer limitations in your life. EnteraGam® for chronic diarrhea will tell you more.

You may also be interested in how changes in the environment of your intestine can be a problem and what you can do about it.

References
  1. Stefano G, Vaziri H, eds. Diarrhea: Diagnostic and Therapeutic Advances. New York, NY: Humana Press; 2011.
  2. EnteraGam [product information]. Ankeny, IA: Entera Health, Inc.; October 2016.
  3. Petschow BW, Burnett B, Shaw AL, Weaver EM, Klein Serum-derived bovine immunoglobulin/protein isolate: postulated mechanism of action for management of enteropathy. Clin Exp Gastroenterol. 2014;7:181-190.
  4. Gasbarrini A, Lauritano EC, Garcovich M, Sparano L, Gasbarrini New insights into the pathophysiology of IBS: intestinal microflora, gas production and gut motility. Eur Rev Med Pharmacol Sci. 2008;12 Suppl 1:111-117.
  5. Juckett G, Trivedi R. Evaluation of chronic diarrhea. Am Fam Physician. 2011;84(10):1119-1126.

Intended Use

EnteraGam® is a medical food product intended for the dietary management of chronic diarrhea and loose stools. EnteraGam® must be administered under medical supervision.

Important Safety Information:

EnteraGam® contains beef protein: therefore, patients who have an allergy to beef or any other component of EnteraGam® should not take this product. EnteraGam® has not been studied in pregnant women, in women during labor and delivery, or in nursing mothers. The choice to administer EnteraGam® during pregnancy, labor and delivery, or to nursing mothers is at the clinical discretion of the prescribing physician.

EnteraGam® does not contain any milk-derived ingredients such as lactose, casein, or whey. EnteraGam® is gluten-free, dye-free, and soy-free.

Please see full Product Information

To report suspected adverse reactions, contact Entera Health, Inc. at 1-855-4ENTERA (1-855-436-8372), or the FDA at 1-800-FDA-1088 (1-800-332-1088) or www.fda.gov/medwatch.